Endo – Thyroid

Master answer

• Metabolic:
  • Increased basal metabolic rate (metabolic rate increased in nearly all cells)
  • Carbohydrate
    • ↑absorption
    • ↑gluconeogenesis
    • ↑insulin secretion
    • ↑cellular glucose uptake
  • Lipid
    • ↑absorption
    • ↑resorption from adipose tissue
      • → ↑plasma free fatty acids
    • ↑removal of cholesterol by liver (excreted in bile)
      • → ↓plasma cholesterol
  • Protein
    • ↑muscle catabolism
• CVS:
  • +ve inotropy
  • +ve chronotropy
  • Vasodilation (so BP stays roughly the same)
• Resp:
  • ↑VT and ↑RR
    • Due to higher metabolic rate
• Neuro:
  • Lowered seizure threshold
  • Anxiety
  • Insomnia
• GIT:
  • Increased motility
• MSK:
  • ↑contractility
  • Late effects of protein catabolism -> muscle wasting and weakness

Mooney 2016

Answer by Mooney